diabetes (diabetes mellitus)
(dI-uh-bE-tEs), (dI-uh-bE-tEs mel-I-tus)
AA metabolic disease in which carbohydrate utilization is reduced while lipid and protein usage is enhanced; it is caused by a complete or relative deficiency of insulin and is characterized in more severe cases by chronic hyperglycemia, glycosuria, water and electrolyte loss, ketoacidosis, and coma. Long-term complications include: development of disorders of the nervous system, eyes and kidneys; generalized degenerative changes in large and small blood vessels; and an increased susceptibility to infection.